THE SINGLE BEST STRATEGY TO USE FOR NR1-SITE

Using this solution, Kalbaugh et al. assigned affinity and efficacy roles to positions while in the LBDs in the NR1 and NR2A NMDAR subunits. In situ mutation of residues in direct contact with certain ligand influenced both of those efficacy and affinity, whilst positions that stabilize the shut cleft conformation without a direct ligand interactio